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Selank

May 22, 2024Promising
6/10

Purrptide digest

Most anxiety drugs work by turning your brain's volume knob way down. Selank is the rare one that just… tunes the station. It calms you down while your brain keeps working at full speed. Like noise-cancelling headphones for your nervous system, except they also help you focus. Russia approved it in 2009. Make of that what you will β€” but it works through pathways that Western science respects.

What this means for you

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If you care about weight/health

Anxiety relief that doesn't fog your brain or chain you to a prescription. If that sounds too good to be true, that's exactly what makes it worth watching.

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If you're a clinician

It calms without sedating, which is genuinely rare. Mechanistically differentiated from everything currently approved β€” worth knowing about.

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If you're a researcher

Anxiety goes down AND brain-growth factors go up at the same time. That combo should not work as cleanly as it apparently does.

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If you follow biotech

A non-sedating, non-addictive anxiolytic is a multi-billion dollar gap in the US market. Nobody's run a proper Western trial yet. That's the opportunity.

SE
Semenova et al.
Institute of Molecular Genetics, Russian Academy of Sciences
View profile β†’

For the nerds

Selank modulates gene expression and anxiety-like behaviour in stressed rats

Psychopharmacology Β· DOI: 10.1007/s00213-011-2470-7

Read full paper on PubMed β†’