Tirzepatide
November 12, 2024Paradigm Shift
9/10
Purrptide digest
Your brain has an 'I'm full' button. Tirzepatide duct-tapes TWO of them in the ON position at once. People lost up to 22% of their body weight. That's like losing an entire carry-on suitcase of fat without going to the gym. Eli Lilly literally ran out of stock. When a pharma company sells out, you know it's real.
What this means for you
🏃
If you care about weight/health
Closest thing to a cheat code for weight loss that actually works. Not magic — just the best tool we've seen in 30 years.
🩺
If you're a clinician
Your patients are already googling this. The 22% loss number is real and repeatable.
🔬
If you're a researcher
Nobody fully understands WHY two receptors work 5x better than one. That mystery is the interesting part.
💸
If you follow biotech
Eli Lilly's stock went on a rocket ship. A $50B market appeared overnight.
JA
Jastreboff et al.
Eli Lilly and Company
For the nerds
Tirzepatide Once Weekly for the Treatment of Obesity
New England Journal of Medicine · DOI: 10.1056/NEJMoa2206038
Read full paper on PubMed →